Liquid Chromatography Testing

Liquid chromatography (LC) refers to analytical laboratory techniques used to separate and quantify cannabinoids and terpenes in cannabis plant material. Common variants include high-performance liquid chromatography (HPLC) and ultra-high-performance liquid chromatography (UHPLC), which use solvent-based separation methods under controlled conditions. Unlike gas chromatography, LC methods do not require heat and therefore preserve heat-sensitive compounds in their native form, making them valuable for accurate cannabinoid profiling. LC testing is widely adopted by breeding programs and regulatory laboratories to measure cannabinoid ratios, minor cannabinoid presence, and terpene composition. Results from LC analysis inform strain selection, breeding decisions, and compliance documentation.

Breeders rely on LC testing data to verify cannabinoid phenotypes, track minor cannabinoid expression (CBG, CBC, CBDV), and document consistent chemotype profiles across generations. Detailed LC profiles support selective breeding for specific cannabinoid ratios and terpene combinations.