Terpene Sesquiterpenes

Sesquiterpenes are a large class of volatile organic compounds found in cannabis and many plants, characterized by a 15-carbon skeleton (C15H24). These molecules are heavier and less volatile than monoterpenes, contributing to the later-stage aroma profile during flower maturation and curing. Common sesquiterpenes in cannabis include caryophyllene, humulene, and β-myrcene variants, often associated with woody, spicy, earthy, or herbal notes. Breeders and chemists study sesquiterpene ratios as markers of cultivar stability and phenotype expression. Sesquiterpene-rich profiles are frequently documented in indica-leaning and landrace genetics.

Sesquiterpene expression is often used by breeders as a secondary selection criterion to stabilize desired aroma profiles across generations. Preservation of sesquiterpene-dominant phenotypes requires attention to curing conditions and storage, as these compounds are prone to oxidation and microbial degradation over time.