Charlottes Web

Charlotte's Web is a high-CBD cannabis strain family that emerged from the breeding work of the Stanley brothers in Colorado around 2011. The strain gained prominence through its use in pediatric epilepsy research and advocacy, though medical claims remain outside this encyclopedia's scope. Genetically, Charlotte's Web typically expresses a 20:1 or higher CBD-to-THC ratio, making it a notable reference point in the CBD-dominant breeding category. The strain's genetics incorporate Indica and Sativa ancestry, with lineage records frequently reporting contributions from Mexican and Afghan heritage stock. Charlotte's Web and its derivatives have become foundational genetics for breeders developing high-CBD cultivars intended for industrial and research applications.

Breeders working in the CBD-dominant category commonly use Charlotte's Web genetics as a parent line to stabilize cannabinoid ratios and CBD expression. The family's documented low-THC phenotype has been instrumental in developing commercially viable high-CBD strains for regulated markets.