Cannabigerol Synthase
Cannabigerol synthase (CGS) is the enzyme responsible for synthesizing cannabigerol (CBG), a foundational cannabinoid precursor in cannabis biochemistry. CGS catalyzes the first committed step in cannabinoid biosynthesis, converting geranylpyrophosphate and olivetolic acid into cannabigerol. From CBG, downstream enzymes produce THC, CBD, and other major cannabinoids through distinct enzymatic pathways. Genetic variation in CGS expression and activity significantly influences the cannabinoid profile a plant develops. Understanding CGS function is central to cannabis breeding programs seeking to manipulate final cannabinoid ratios and develop high-CBG cultivars.
Cannabigerol Synthase strains
No strains tagged into Cannabigerol Synthase yet — they'll appear here as breeders submit lineage records under this family.
Cannabigerol synthase (CGS) is the enzyme responsible for synthesizing cannabigerol (CBG), a foundational cannabinoid precursor in cannabis biochemistry. CGS catalyzes the first committed step in cannabinoid biosynthesis, converting geranylpyrophosphate and olivetolic acid into cannabigerol. From CBG, downstream enzymes produce THC, CBD, and other major cannabinoids through distinct enzymatic pathways. Genetic variation in CGS expression and activity significantly influences the cannabinoid profile a plant develops. Understanding CGS function is central to cannabis breeding programs seeking to manipulate final cannabinoid ratios and develop high-CBG cultivars.
Breeders studying CBG-dominant phenotypes focus on CGS expression levels and efficiency, as enhanced or prolonged CGS activity can shift cannabinoid distribution toward CBG accumulation. Selection for high-CBG genetics requires monitoring both enzyme activity and upstream precursor availability to achieve consistent CBG-rich plants.
Educational reference · Cultivar metadata only · No medical claims